Research Article
HEIH Promotes Malignant Progression of Gastric Cancer by Regulating STAT3-Mediated Autophagy and Glycolysis
Figure 4
HEIH promotes the development of gastric cancer by inhibiting miR-4500. (a) Knockdown of HEIH can upregulate the expression of miR-4500. (b) Analysis of cell proliferation ability after cotransfection with HEIH-specific siRNA or miR-4500 inhibitor. (c) After cotransfection with HEIH-specific siRNA or miR-4500 inhibitor, cell colony formation experiment. (d) Transwell cell invasion test after cotransfection with HEIH-specific siRNA or miR-4500 inhibitor. (e) qRT-PCR detects the expression level of Twist1 in the cell line after cotransfection. (f) qRT-PCR detects the expression level of N-cadherin in the cell line after cotransfection. (g) qRT-PCR detects the expression level of E-cadherin in the cell line after cotransfection. and .
(a) |
(b) |
(c) |
(d) |
(e) |
(f) |
(g) |