Identifying Differentially Expressed tRNA-Derived Small Fragments as a Biomarker for the Progression and Metastasis of Colorectal Cancer

<div>TGF-<i>β</i> induces EMT in human colorectal cancer cells. (a) Phase-contrast images of HT29 cells. Human colorectal cancer cell HT29 was starved in 0.5% FBS for 8 h. After starvation, cells were stimulated with TGF-<i>β</i> in 0.5% FBS medium for another 48 h to establish the cellular model of EMT. (b) Total RNA was extracted and detected by qRT-PCR for indicated genes in HT29 cells treated with TGF-<i>β</i>. All of the genes are involved in EMT. 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Disease Markers

fig1

Figure 1

Figure 1: Identifying Differentially Expressed tRNA-Derived Small Fragments as a Biomarker for the Progression and Metastasis of Colorectal Cancer 