Research Article
Identifying Differentially Expressed tRNA-Derived Small Fragments as a Biomarker for the Progression and Metastasis of Colorectal Cancer
Table 2
Association of tRF-VAL-TCA-002 expression with clinical and pathologic features in CRC patients.
| | Parameter | Total | tRF-VAL-TCA-002 | | | | Low | High |
| | Age (years) | | | | 25 | 0.114 | | ≤50 | 16 | 3 | 13 | | >50 | 52 | 15 | 37 | | Gender | | | | 0.011 | 0.917 | | Female | 22 | 6 | 16 | | Male | 46 | 12 | 34 | | Tumor size (cm) | | | | 1.551 | 0.213 | | <4 | 33 | 11 | 22 | | ≥4 | 35 | 7 | 28 | | Tumor differentiation | | | | 2.175 | 0.014 | | Well/moderate | 37 | 12 | 25 | | Poor | 31 | 6 | 25 | | Distant metastasis | | | 6.567 | 0.01 | | Negative | 28 | 12 | 16 | | Positive | 40 | 6 | 34 | | Clinical stage (TNM) | | | 10.55 | 0.001 | | I~II | 24 | 12 | 12 | | III~IV | 44 | 6 | 38 |
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