Overexpression of BRINP3 Predicts Poor Prognosis and Promotes Cancer Cell Proliferation and Migration via MAP4 in Osteosarcoma

Table 1

Correlation between clinicopathological features and BRINP3 expression.

Characteristics	BRINP3 protein expression		value
	Low expression	High expression
Age			0.805
<20	25 (75.8%)	42 (71.2%)
≥20	8 (24.2%)	17 (28.8%)
Gender			0.028
Female	19 (57.6%)	20 (33.9%)
Male	14 (42.4%)	39 (66.1%)
Tumor size			0.13
<5	3 (9.1%)	1 (1.7%)
≥5	30 (90.9%)	58 (98.3%)
Tumor position			0.975
Femur	15 (45.5%)	30 (50.8%)
Tibia	8 (24.2%)	13 (22.0%)
Humerus	4 (12.1%)	7 (11.9%)
Fibulars	2 (6.1%)	2 (3.4%)
Irregular bone	4 (12.1%)	7 (11.9%)
Histologic grade			<0.001
Low grade	24 (72.7%)	14 (23.7%)
High grade	9 (27.3%)	45 (76.3%)
Metastasis			0.081
Present	20 (60.6%)	23 (39.0%)
Absent	9 (27.3%)	30 (50.8%)
Unknown	4 (12.1%)	6 (10.2%)
Recurrence			<0.001
Positive	4 (12.1%)	51 (86.4%)
Negative	26 (78.8%)	5 (8.5%)
Unknown	3 (9.1%)	3 (5.1%)