Gene-Based Network Analysis Reveals Prognostic Biomarkers Implicated in Diabetic Tubulointerstitial Injury

Figure 9

(a) Volcano plot indicating the upregulated and downregulated genes in tubulointerstitial samples from patients with DN. The horizontal axis represents the fold-change between healthy living donors and patients with DN. The vertical axis represents the values of the differences between healthy donors and patients with DN, as determined using Student’s -test. The genes most relevant for DN are highlighted in red (2-fold change) or blue (2-fold change). Labels were overlapped genes between DEGs and hub genes choosing from WGCNA. (b) LASSO Cox regression analysis.

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