Molecular Polymorphisms of Vascular Endothelial Growth Factor Gene and Bronchopulmonary Dysplasia in Very Low Birth Weight Infants

Table 1

Clinical characteristics of study population.

	Controls		BPD
		%		%
	49		33		—
Gender (male/female)	24/25	48.9%	20/13	60.6%	0.29
Patients with birth  g	4	8.1%	25	75.7%	0.00001
Apgar score (<5 at 1 min and <7 at 5 min)	11	22.4%	22	66.6%	0.00001
Preeclampsia (PE)	9	18.3%	10	30.3%	0.18
Premature rupture of membranes (Pprom)	16	32.6%	13	39.3%	0.53
Chorioamnionitis (CA)	6	12.2%	6	18.1%	0.39
Patent ductus arteriosus (PDA)	1	2.0%	12	36.3%	0.00001
Mechanical ventilation during the first 3 days of life	22	44.8%	30	90.9%	0.00001
Nasal continuous positive pressure (ncPAP)	22	44.8%	22	66.6%	0.0523
Synchronized intermittent mechanical ventilation (SIMV)	10	20.4%	22	66.6%	0.00001
Surfactant therapy	12	24.4%	22	66.6%	0.00001
Diuretic therapy	0	—	18	54.5%	—
Antenatal steroid treatment in mother	21	42.8%	12	36.3%	0.49