Research Article
Activated Partial Thromboplastin Time and Mortality in Coronary Artery Bypass Grafting Patients
Table 1
Characteristics of the study patients before PSM.
| | Characteristics | Before PSM | | Total () | () | () | value |
| | Demographics | | | | | | Age, years | 68.8 (60.0-76.4) | 67.5 (59.0-75.0) | 72.7 (64.7-79.4) | <0.001 | | Gender, female | 717 (26.5) | 464 (23.1) | 253 (36.2) | <0.001 | | Ethnicity, (%) | | | | 0.506 | | White | 1789 (66.1) | 1336 (66.6) | 453 (64.8) | | | Black | 71 (2.6) | 51 (2.5) | 20 (2.9) | | | Asian | 44 (1.6) | 28 (1.4) | 16 (2.3) | | | Hispanic | 44 (1.6) | 31 (1.5) | 13 (1.9) | | | Other | 758 (28.0) | 561 (28.0) | 197 (28.2) | | | Comorbidities, (%) | | | | | | Hypertension | 1952 (72.1) | 1472 (73.3) | 480 (68.7) | 0.020 | | DM | 1010 (37.3) | 793 (39.5) | 217 (31.0) | <0.001 | | Peripheral vascular disease | 355 (13.1) | 243 (12.1) | 112 (16.0) | 0.010 | | MI | 511 (18.9) | 348 (17.3) | 163 (23.3) | 0.001 | | CHF | 677 (25.0) | 430 (21.4) | 247 (35.3) | <0.001 | | Chronic pulmonary disease | 356 (13.2) | 246 (12.3) | 110 (15.7) | 0.023 | | Renal failure | 202 (7.5) | 129 (6.4) | 73 (10.4) | 0.001 | | Liver disease | 39 (1.4) | 24 (1.2) | 15 (2.1) | 0.103 | | Obesity | 124 (4.6) | 102 (5.1) | 22 (3.1) | 0.045 | | 24 h vital signs | | | | | | Mean SBP, mmHg | 111.4 (105.8-119.0) | 111.0 (105.9-118.3) | 112.8 (105.6-121.1) | 0.022 | | Mean DBP, mmHg | 56.3 (52.7-60.6) | 56.3 (52.7-60.4) | 56.3 (52.4-61.2) | 0.597 | | Mean HR, beats/min | 85.1 (79.2-91.1) | 85.4 (79.9-91.4) | 84.2 (77.3-90.1) | <0.001 | | Mean respiratory rate, beats/minute | 16.7 (15.0-18.8) | 16.8 (15.1-18.8) | 16.5 (14.8-18.7) | 0.051 | | Mean temperature, °C | 36.9 (36.6-37.2) | 36.9 (36.6-37.2) | 36.8 (36.5-37.2) | <0.001 | | Mean SpO2, % | 98.3 (97.3-99.0) | 98.3 (97.4-99.0) | 98.2 (97.3-98.9) | 0.111 | | Laboratory parameters | | | | | | WBC, 109/L | 11.8 (9.1-15.3) | 12.2 (9.4-15.6) | 10.9 (8.3-13.8) | <0.001 | | Hemoglobin, g/dL | 10.0 (8.9-11.2) | 10.0 (9.0-11.1) | 9.9 (8.7-11.3) | 0.351 | | Platelet, 109/L | 156.5 (122.0-203.0) | 158.0 (125.0-202.0) | 152.0 (108.0-206.0) | 0.002 | | Sodium, mmol/L | 137.0 (135.0-139.0) | 137.0 (135.0-139.0) | 137.0 (134.0-139.0) | 0.610 | | Potassium, mmol/L | 4.3 (3.9-5.0) | 4.4 (3.9-5.0) | 4.2 (3.8-4.8) | 0.001 | | Creatinine, μmol/L | 0.8 (0.7-1.0) | 0.8 (0.7-1.0) | 0.9 (0.7-1.1) | <0.001 | | Glucose, mg/dL | 135.0 (114.0-164.0) | 136.0 (114.0-164.0) | 135.0 (113.0-165.0) | 0.927 | | Management, (%) | | | | | | Mechanical ventilation | 2610 (96.5) | 1938 (96.6) | 672 (96.1) | 0.686 | | CRRT | 45 (1.7) | 17 (0.8) | 28 (4.0) | <0.001 | | Vasopressor use | 2342 (86.5) | 1743 (86.8) | 599 (85.7) | 0.481 | | Severity of illness, points | | | | | | SOFA | 4.0 (3.0-6.0) | 4.0 (3.0-6.0) | 5.0 (3.0-7.0) | <0.001 | | SAPS II | 33.0 (27.0-40.0) | 32.0 (26.0-39.0) | 36.0 (29.0-43.0) | <0.001 | | APTT, second | 35.2 (30.3-44.3) | 32.7 (29.1-36.5) | 54.8 (47.7-69.5) | <0.001 |
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PSM: propensity score matching; DM: diabetes mellitus; MI: myocardial infarction; CHF: congestive heart failure; SBP: systolic blood pressure; DBP: diastolic blood pressure; HR: heart rate; WBC: white blood cell; CRRT: continuous renal replacement therapy; SOFA: Sequential Organ Failure Assessment; SAPS II: Simplified Acute Physiology Score II; APTT: activated partial thromboplastin time.
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