Integrative Analysis of m6A RNA Methylation Regulators and the Tumor Immune Microenvironment in Non-Small-Cell Lung Cancer

<div>Landscape of genetic variation in m6A regulators in NSCLC. (a) The graph depicts the frequency of CNV alterations in 20 m6A regulators in NSCLC, with loss (gain) frequencies marked with green (red) dots. (b) Mutation sites of m6A regulators on 23 chromosomes. (c) Mutation frequency of m6A regulators in NSCLC, with each column representing an individual patient, the number and bar graph on the right representing mutation frequency of each regulator, and the stacked bar graph below representing transformation of each sample. (d) Regulation between m6A mRNA expression levels. Tumor, red; normal tissue, blue. 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Disease Markers

fig2

Figure 2

Figure 2: Integrative Analysis of m6A RNA Methylation Regulators and the Tumor Immune Microenvironment in Non-Small-Cell Lung Cancer 