Integrative Analysis of m6A RNA Methylation Regulators and the Tumor Immune Microenvironment in Non-Small-Cell Lung Cancer

Figure 3

Patterns of m6A modifications mediated by 20 m6A regulators in NSCLC. (a) Interactions of m6A regulators in NSCLC. The size of each circle represents the survival impact of each m6A regulator. The line connecting the m6A regulator and regulator shows the interaction between them. The thickness of the line represents the strength of the correlation between regulators. The value was calculated by log-rank test. (b) Consensus clustering of NSCLC patients for . (c) Consensus clustering CDF for . (d) The CDF curve of consensus clustering. (e) The tracking plot for to 9. (f) The value of the Kaplan–Meier curve was 0.025, indicating a significant difference in survival between the two m6A modification modes. The survival prognosis of cluster B was better than that of cluster A.

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