Altered Functional Connectivity in Pain-Related Brain Regions and Its Correlation with Pain Duration in Bone Metastasis with Cancer Pain

Figure 3

Statistical differences of functional connectivity in intergroup comparisons. (a) Shows the comparison between CP+ and CP−. (b) Shows comparison between CP− and HC. CP+: lung cancer patients with bone metastases suffering from cancer pain; CP−: lung cancer patients without pain-related complaints; HC: health controls; DLPFC: dorsal lateral prefrontal cortex; SII: secondary somatosensory cortex; ACC: anterior cingulate cortex; THA: thalamus; AMY: amygdala; L: left; R: right.

(a)

(b)