Scutellarin Improves Type 2 Diabetic Cardiomyopathy by Regulating Cardiomyocyte Autophagy and Apoptosis

Figure 3

SCU suppresses the apoptotic signaling pathway in the T2DC model. (a) SCU suppressed the mRNA expression of caspase-3, caspase-8, caspase-9, and caspase-12 by RT-qPCR assay. (b) SCU suppressed the activity of caspase-3, caspase-8, caspase-9, and caspase-12 by western blot detection. (c) SCU inhibited the protein expression of procaspase-3, procaspase-8, procaspase-9, and procaspase-12 by western blot assay. The values shown are the (SEM) of the data from three independent experiments. ^#Significant compared with the control group alone, . Significant compared with the model group alone, .

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