Signature and Molecular Mechanism of Mitochondrial Energy Metabolism Pathway-Related Genes in Lung Adenocarcinoma

<div>SNV and CNV analysis based on MEMP key genes. (a) TCGA-LUAD patient waterfall plots showing the mutation landscapes of MEMP key genes. (b) Comutation analysis of top25 with the highest mutation frequency in MEMP gene. (c) The majority of MEMP-related genes were amplified in the TCGA-LUAD patients. (d) Boxplots indicating the copy number amplification and the normal had significant differences of MEMP key genes (EFNA3, GPI, SLC25A10, and PC).</div>

Disease Markers

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Figure 2

Figure 2: Signature and Molecular Mechanism of Mitochondrial Energy Metabolism Pathway-Related Genes in Lung Adenocarcinoma 