Review Article

Prognostic and Clinical Significance of Aspartate Aminotransferase-to-Lymphocyte Ratio Index in Individuals with Liver Cancer: A Meta-Analysis

Table 3

Correlations of ALRI and clinical factors in patients with hepatocellular carcinoma.

CharacteristicsNo. of studiesNo. of patientsEffects modelOR (95% CI)Heterogeneity
2 (%)

Sex, male vs. female61995Random1.32 (1.02-1.70)0.03500.613
Age, years, >60 vs. ≤603475Random0.89 (0.56-1.43)0.63700.630
HBsAg, positive vs. negative51566Random1.26 (0.95-1.67)0.10400.410
AFP, ng/ml, >400 vs. ≤40041418Random1.45 (0.89-2.37)0.13671.90.014
Cirrhosis, yes vs. no51566Random1.68 (1.01-2.81)0.046630.029
Tumor size, ≥5 cm vs. <5 cm51566Random2.25 (1.31-3.88)0.00381<0.001
Tumor number, multiple vs. single41360Random1.19 (0.87-1.64)0.27100.685
TNM stage, III-IV vs. I-II41246Random1.94 (0.97-3.90)0.06287.6<0.001
PVTT, yes vs. no41069Random2.50 (1.52-4.11)<0.00147.40.127
Distant metastasis, yes vs.no3878Random1.72 (1.05-2.82)0.03100.472