[Retracted] Apelin Alleviates Meniscus Endothelial Cell Apoptosis in Osteoarthritis

Figure 1

Identification of endothelial cells in meniscus biopsies. (a) scRNA-seq analysis of cellularity in meniscus: the left UMAP plot shows nine clusters across 3577 meniscus cells isolated from controls, and the right UMAP plot shows 11 clusters across 3256 meniscus cells isolated from patients with OA. (b) Violin plots showing the expression of endothelial cell feature genes (CD93, CDH5, and PECAM1) and monocyte/macrophage feature genes (CD14 and MS4A7). (c) Left pie plot showing the proportion of nine clusters in controls and the right pie plot showing the proportion of nine clusters in patients with OA. (d) Flow cytometry analysis gating on endothelial cells. Endothelial cells were gated on 7-AAD-CD45-PECAM1+ cells. cells were acquired from each sample. (e) Dot plot showing statistical analysis of the absolute number of meniscus endothelial cells between controls and patients with OA. Each dot represents one readout. Data represent four independent experiments. .

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