Alteration in the Immune Microenvironment Based on APC Status in MSS/pMMR Colon Cancer

Figure 6

Histology (H&E: hematoxylin and eosin) and immunohistochemistry showing four different expression patterns of CD8 and PD-L1 in the representative case. We identified patients with 22 APC-mt/MSS (left) and 20 APC-wt/MSS (right) colon cancer. APC-wt/MSS is significantly higher than APC-mt/MSS in the positive rate and the degrees of positive expression for CD8 and PD-L1 with immunostaining.