Research Article

Echium amoenum L. Ethanol Extract Protects Retinal Ganglion Cell after Glutamate and Optic Nerve Crush Injury

Figure 4

E. amoenum ethanol extract suppressed the inflammation response triggered by optic nerve crush (ONC) injury. (a) Retinas from different groups were harvested on day 7 after ONC and subjected to frozen-section immunostaining with Iba1. (b) Quantification of microglia in the retina. (c) Expression of p-p65 in different groups determined by immunoblotting. (d) Quantification of the p-p65 levels in each group. (e) Retinas from different groups were harvested 7 days after ONC and subjected to real-time PCR analysis to determine the relative mRNA levels of IL-6, iNOS, and IL-1β. Data are shown as the (); , , and .
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