lncRNA LEF1-AS1 Acts as a Novel Biomarker and Promotes Hypopharyngeal Squamous Cell Carcinoma Progression and Metastasis by Targeting the miR-221-5p/GJA1 Axis

<div>LEF1-AS1 positively regulates cell migration, invasion, and EMT process. (a) Wound healing assays in LEF1-AS1 overexpressed or silenced FaDu cells. (b) Relative migration rate in (a). (c) Transwell experiments for cell migration and invasion detection. (d, e) Relative migrated (d) or invaded (e) FaDu cell number in (c). (f) GSEA analysis of EMT gene sets based on LEF1-AS1 expression information in TCGA. (g) Western blot analysis of E-cadherin, N-cadherin, and vimentin in LEF1-AS1 overexpressed or silenced FaDu cells. 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Disease Markers

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Figure 3

Figure 3: lncRNA LEF1-AS1 Acts as a Novel Biomarker and Promotes Hypopharyngeal Squamous Cell Carcinoma Progression and Metastasis by Targeting the miR-221-5p/GJA1 Axis 

Figure 3 | lncRNA LEF1-AS1 Acts as a Novel Biomarker and Promotes Hypopharyngeal Squamous Cell Carcinoma Progression and Metastasis by Targeting the miR-221-5p/GJA1 Axis 