Deguelin Attenuates Non-Small-Cell Lung Cancer Cell Metastasis by Upregulating PTEN/KLF4/EMT Signaling Pathway

<div>Deguelin upregulates PTEN and KLF4 expression in NSCLC cells. (a) The expression levels of PTEN and KLF4 in A549 cells induced by deguelin (25 <i>μ</i>M) at different times compared to controls treated by PBS. (b) The expression levels of PTEN and KLF4 in PC9 cells induced by deguelin at different times compared to controls treated by PBS. <i>β</i>-Actin was used as an internal control. All experiments were repeated at least in triplicate.</div>

Disease Markers

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Figure 1

Figure 1: Deguelin Attenuates Non-Small-Cell Lung Cancer Cell Metastasis by Upregulating PTEN/KLF4/EMT Signaling Pathway 