Deguelin Attenuates Non-Small-Cell Lung Cancer Cell Metastasis by Upregulating PTEN/KLF4/EMT Signaling Pathway

Figure 2

Determination of PTEN-siR/overexpression and KLF4-siR/overexpression in NSCLC cells at different times. (a) The expression levels of PTEN and KLF4 in A549 cells treated by PTEN-siR/overexpression and KLF4-siR/overexpression at different times compared to controls treated by PBS, respectively. (b) The expression levels of PTEN and KLF4 in PC9 cells treated by PTEN-siR/overexpression and KLF4-siR/overexpression at different times compared to controls treated by PBS, respectively. β-Actin was used as an internal control. All experiments were repeated at least in triplicate.