Deguelin Attenuates Non-Small-Cell Lung Cancer Cell Metastasis by Upregulating PTEN/KLF4/EMT Signaling Pathway

<div>Deguelin inhibited tumor growth by upregulating PTEN and KLF4 expressions in mice model with NSCLC cells. (a) On day 21, the tumors were carefully dissected from the mice, and the tumor size was measured. (b) The expression levels of KLF4 and PTEN proteins in tumors were detected. (c and d) The relative band intensity of KLF4 and PTEN in tumors were detected. <i>β</i>-Actin was used as an internal control. 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Disease Markers

fig6

Figure 6

Figure 6: Deguelin Attenuates Non-Small-Cell Lung Cancer Cell Metastasis by Upregulating PTEN/KLF4/EMT Signaling Pathway 