Research Article

A Liver Stiffness Measurement-Based Nomogram Predicts Variceal Rebleeding in Hepatitis B-Related Cirrhosis

Table 2

Clinical characteristics between the rebleeding and nonrebleeding groups.

No rebleeding ()Rebleeding () value

Age (years)49.82 (12.99)53.17 (12.09)0.055
Male149 (68.66)53 (73.61)0.379
BMI21.86 (3.04)22.4 (3.13)0.193
Portal vein diameter (cm)1.4 (1.3-1.6)1.5 (1.3-1.6)0.100
Use of NSBB155 (71.4)34 (47.2)<0.001
Baseline LSM (kPa)13.3 (9.89-16.9)18.8 (13.5-23.4)<0.001
WBC (×109/L)4.65 (2.28)3.48 (2.08)<0.001
HB (g/L)103 (27.7)88.9 (24.7)<0.001
Platelet count (×109/L)104 (74.4)65.9 (38.4)<0.001
PT (second)13.4 (12.5-14.8)14.0 (12.7-14.8)0.235
INR1.19 (1.10-1.33)1.25 (1.14-1.34)0.058
Fibrinogen (g/L)1.81 (1.37-2.34)1.56 (1.16-1.93)0.012
Albumin (g/L)35.0 (6.29)35.1 (5.42)0.826
Total bilirubin18.9 (12.3-31.9)20.0 (13.7-28.8)0.974
ALT (U/L)21.0 (15.8-31.8)25.0 (17.0-45.0)0.07
AST (U/L)31.5 (22.8-47.5)36.0 (27.0-55.0)0.043
Cr (μmol/L)5.98 (5.25)5.65 (5.02)0.634
BUN (mmol/L)65.0 (56.0-77.2)6.2 (55.3-80.6)0.887
MELD score9.07 (8.13-11.4)9.54 (8.31-11.3)0.151
Child-Pugh class0.229
 A205 (70.9%)56 (19.7%)
 B12 (4.2%)16 (5.2%)

value < 0.05 indicates a significant difference between the cohorts presenting with rebleeding event versus no rebleeding. BMI: body mass index; HB: hemoglobin; WBC: white blood cell; PVT: portal vein thrombosis; ALT: alanine aminotransferase; AST: aspartate aminotransferase; ALP: alkaline phosphatase; GGT: gamma-glutamyl transpeptidase; LSM: liver stiffness measurement; INR: international normalized ratio; Cr: creatinine BUN: blood urea nitrogen; PT: prothrombin time.