A Liver Stiffness Measurement-Based Nomogram Predicts Variceal Rebleeding in Hepatitis B-Related Cirrhosis
Table 3
Prognostic factors for rebleeding rate of cirrhosis patients.
Univariate
Multivariate
HR (95% CI)
value
HR (95% CI)
value
Gender
1.267 (0.75-2.14)
0.376
Age (years)
0.987 (0.97-1.003)
0.113
BMI
1.054 (0.981-1.132)
0.153
PVT
0.662 (0.355-1.234)
0.194
Portal vein diameter (cm)
2.458 (1.159-5.211)
0.019
Use of NSBB
0.387 (3.392-0.615)
0.000
0.278 (0.17-0.454)
0.000
Baseline LSM (kPa)
1.03 (1.01-1.049)
0.003
1.026 (1.005-1.048)
0.013
WBC (×109/L)
0.936 (0.853-1.028)
0.169
HB (g/L)
0.983 (0.974-0.992)
0.000
0.986 (0.977-0.995)
0.003
Platelet count (×109/L)
0.988 (0.983-0.994)
0.000
0.993 (0.987-0.999)
0.018
PT (second)
1.015 (0.967-1.066)
0.543
INR
1.006 (0.74-1.368)
0.970
Fibrinogen (g/L)
0.92 (0.714-1.187)
0.522
Albumin (g/L)
1.005 (0.968-1.043)
0.791
Total bilirubin (μmol/L)
1 (0.988-1.011)
0.934
ALT (IU/L)
0.997 (0.991-1.003)
0.379
AST (IU/L)
0.998 (0.993-1.003)
0.372
GGT (IU/L)
0.997 (0.995-1)
0.062
ALP (IU/L)
0.997 (0.994-1)
0.08
BUN (mmol/L)
0.987 (0.935-1.042)
0.653
Cr (μmol/L)
0.996 (0.987-1.006)
0.456
MELD score
1.048 (0.981-1.12)
0.161
Child-Pugh class
A
Ref
B
0.692 (0.399-1.2)
0.190
All variables were entered in a forward LR elimination procedure with a value to exit set at >0.10. Empty cells refer to the variables excluded from the multivariable-adjusted logistic regression models. BMI: body mass index; HB: hemoglobin; WBC: white blood cell; PVT: portal vein thrombosis; ALT: alanine aminotransferase; AST: aspartate aminotransferase; ALP: alkaline phosphatase; GGT: gamma-glutamyl transpeptidase; LSM: liver stiffness measurement; INR: international normalized ratio; Cr: creatinine BUN: blood urea nitrogen; PT: prothrombin time.
