Research Article

Paraoxonase-1 (PON-1) Arylesterase Activity Levels in Patients with Coronary Artery Disease: A Meta-Analysis

Table 1

General characteristics of the population enrolled.

AuthorStudy typeCountryCAD, (% male)Non CAD, (% male)Mean age (years)BMI (kg/m2)TC mmol/L [mg/dl]C-HDL mmol/L [mg/dl]TG mmol/L [mg/dl]
CADNon-CADCADNon-CADCADNon-CADCADNon-CADCADNon-CAD

Sun et al. [9]Case-controlChina130 (50)47 (53)

Fridman et al. [13]Case-controlArgentina286 (37)245 (34)NR

Jayakumari et al. [24]Case-controlIndia284 (100)245 (100)NR[][][][][]

Mohamed et al. -[25]Retrospective cohortEgypt150 (79)50 (52)NR

Shekhanawa et al. [26]Cross-sectionalIndia60 (67)50 (58)NRNRNRNRNRNR

Shen et al. [27]Cross-sectionalChina144 (75)69 (54)1

Kuchta et al. [28]Cross-sectionalPoland105 (39)45 (44)[][][][]107 (SD NR)102 (SD NR)

Januszek et al. [29]Case-controlPoland53 (100)53 (100)

Sun et al. [9]Case-controlChina123 (63)63 (44)NRNR

Variji et al. [30]Case-controlIran126 (66)203 (52)NRNR

van Himbergen et al. [14]Case-cohortNetherlands211 (NR)1527 (NR)NRNRNRNR

Lu et al. [15]Case-control

No DM cohort-China88 (66)90 (57)NRNR

IFG cohort-China62 (100)90 (57)NRNR

DM cohort-China46 (57)90 (57)NRNR

Ferrè et al. [16]Case-controlSpain215 (100)215 (100)

Wang et al. [17]Case-controlChina474 (100)475 (100)

Kerkeni et al. [18]Case-controlSpain100 (74)120 (73)

Rodríguez-Esparragón et al. [19]Case-controlSpain304 (78)315 (74)

James et al. [20]Cross-sectionalSwiss137 (76)273 (64)
Itahara et al. [21]Case-controlJapan96 (59)136 (52)[][][][]

Rahmani et al. [22]Cross-sectionalIran
DM cohort89 (57)73 (52)[][][]
No DM cohort89 (57)73 (52)[][][][][][]

Suehiro et al. [23]Case-controlJapan81 (62)103 (52)[][][]

CAD: coronary artery disease; BMI: body mass index; TC: total cholesterol; HDL: high-density lipoproteins; TG: triglycerides; DM: diabetes mellitus; IFG: impaired fasting glucose. The lipidic profile is presented with the measure’s unit used in the original manuscript. vs controls; vs. controls.