Association between Phenotypic Age and Mortality in Patients with Multivessel Coronary Artery Disease

Figure 4

Receiver-operating characteristic curves for all-cause mortality. Receiver-operating characteristic curve presents that PhenoAge predicted risk of mortality better than CA (AUC: 0.705 vs. 0.654, ). It was only when PhenoAge, demographics, clinical and analytical parameters, and disease count were all included in a single model (model 5+PhenoAge) that the AUC started to significantly exceed the AUC for PhenoAge alone (AUC: 0.765 vs. 0.705, ). AUC: area under the curve; CA: chronological age; PhenoAge: phenotypic age; model 5: a model that includes lesion number, revascularization and disease counts, gender, smoking, drinking, body mass index, serum uric acid, creatine kinase, creatine phosphokinase isoenzyme, total cholesterol, triglycerides, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and N-terminal probrain natriuretic peptide.