Association between Phenotypic Age and Mortality in Patients with Multivessel Coronary Artery Disease

Table 3

Area under the curve for all-cause mortality.

Variable	AUC	SE	value	value	for comparison
PhenoAge	0.705	0.033	0.000	Reference	Reference
CA	0.654	0.036	0.000	2.058	0.040
Lesion number	0.517	0.025	0.658	4.479	0.000
Revascularization	0.529	0.039	0.457	3.856	0.000
Disease counts	0.523	0.037	0.304	4.123	0.000
Serum uric acid	0.508	0.043	0.839	3.352	0.000
Total cholesterol	0.487	0.039	0.739	4.174	0.000
Total triglycerides	0.448	0.037	0.176	3.368	0.001
LDL-c	0.474	0.040	0.498	3.808	0.000
HDL-c	0.498	0.041	0.954	3.766	0.000
Creatine kinase	0.428	0.039	0.071	2.769	0.006
CK-MB	0.529	0.038	0.470	3.237	0.001
Model 4	0.540	0.041	0.298	3.382	0.001
Model 4+ CA	0.662	0.035	0.000	1.703	0.089
Model 4+ PhenoAge	0.709	0.033	0.000	0.465	0.642
Model 5	0.740	0.031	0.000	1.233	0.218
Model 5+ CA	0.748	0.032	0.000	1.861	0.063
Model 5+ PhenoAge	0.765	0.031	0.000	3.141	0.002

AUC: area under the curve; SE: standard error; PhenoAge: phenotypic age; CA: chronological age; LDL-c: low-density lipoprotein cholesterol; HDL-c: high-density lipoprotein cholesterol; CK-MB: creatine phosphokinase isoenzyme. Model 4: a model that includes lesion number, revascularization, and disease count. Model 5: a model that includes all the variables in model 4, as well as gender, smoking, drinking, body mass index, serum uric acid, creatine kinase, creatine phosphokinase isoenzyme, total cholesterol, triglycerides, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and N-terminal pro-brain natriuretic peptide.