Ferroptosis-Specific Inhibitor Ferrostatin-1 Relieves H₂O₂-Induced Redox Imbalance in Primary Cardiomyocytes through the Nrf2/ARE Pathway

Figure 3

Ferrostatin-1 inhibited H₂O₂-induced ferroptosis in primary cardiomyocytes. (a) FP1 protein level was detected by WB. (b) FP1 mRNA level was detected by qRT-PCR. (c) Ptgs2 protein level was detected by WB. (d) Ptgs2 mRNA level was detected by qRT-PCR. (e) MDC fluorescence intensity was detected by flow cytometry. (f) The cell apoptosis was detected by TUNEL staining (“” indicates statistical difference from the control group, ; “#” indicates statistical difference from the H₂O₂ group, ; “##” indicates statistical difference from the H₂O₂ group, ).

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