Research Article
Site-Specific Hypermethylation of SST 1stExon as a Biomarker for Predicting the Risk of Gastrointestinal Tract Cancers
Table 2
Correlation of methylation of SST and clinical phenotypes.
| Cancer | Parameter | Group | | 18 | 25 | 34 | 42 | 44 | 85 | 92 | 94 | 97 | 100 | 116 | 127 | 129 | 138 | 148 | AVG |
| EC | Lymphatic metastasis | Positive | 25 | 0.497 | 0.654 | 0.71 | 0.311 | 0.405 | 0.858 | 0.617 | 0.749 | 0.798 | 0.265 | 0.405 | 0.828 | 0.969 | 0.497 | 0.788 | 0.513 | Negative | 17 | Vascular tumor emboli | Positive | 9 | 0.718 | 0.976 | 0.786 | 0.587 | 0.414 | 0.249 | 0.526 | 0.651 | 0.303 | 0.171 | 0.303 | 0.021 | 0.038 | 0.075 | 0.098 | 0.224 | Negative | 33 | Depth of infiltration | Serosa | 26 | 0.141 | 0.451 | 0.92 | 0.201 | 0.268 | 0.041 | 0.478 | 0.668 | 0.099 | 0.035 | 0.094 | 0.4 | 0.51 | 0.316 | 0.355 | 0.641 | Muscular | 13 | Mucosal and submucosal | 3 | Differentiation | Poorly | 5 | 0.014 | 0.17 | 0.15 | 0.381 | 0.381 | 0.827 | 0.937 | 0.897 | 0.803 | 0.977 | 0.195 | 0.289 | 0.143 | 0.247 | 0.346 | 0.289 | Moderately | 21 | High | 16 |
| GC | Lymphatic metastasis | Positive | 64 | 0.471 | 0.013 | 0.073 | 0.257 | 0.578 | 0.339 | 0.821 | 0.804 | 0.91 | 0.958 | 0.566 | 0.869 | 0.848 | 0.487 | 0.301 | 0.924 | Negative | 27 | Vascular tumor emboli | Positive | 57 | 0.961 | 0.993 | 0.085 | 0.608 | 0.426 | 0.348 | 0.724 | 0.931 | 0.879 | 0.583 | 0.688 | 0.737 | 0.831 | 0.7 | 0.403 | 0.974 | Negative | 34 | Depth of infiltration | Serosa | 79 | 0.472 | 0.662 | 0.743 | 0.508 | 0.347 | 0.097 | 0.485 | 0.668 | 0.284 | 0.517 | 0.309 | 0.479 | 0.363 | 0.295 | 0.265 | 0.356 | Muscular | 9 | Mucosal and submucosal | 3 | Differentiation | Poorly | 75 | 0.608 | 0.658 | 0.811 | 0.725 | 0.667 | 0.119 | 0.775 | 0.991 | 0.551 | 0.884 | 0.446 | 0.499 | 0.462 | 0.349 | 0.364 | 0.685 | Moderately | 12 | High | 4 |
| CRC | Lymphatic metastasis | Positive | 38 | 0.658 | 0.56 | 0.939 | 0.81 | 0.923 | 0.758 | 0.721 | 0.973 | 0.758 | 0.651 | 0.21 | 0.272 | 0.321 | 0.285 | 0.06 | 0.63 | Negative | 42 | Vascular tumor emboli | Positive | 11 | 0.917 | 0.273 | 0.743 | 0.939 | 0.994 | 0.227 | 0.534 | 0.905 | 0.85 | 0.917 | 0.553 | 0.66 | 0.691 | 0.463 | 0.796 | 0.917 | Negative | 69 | Depth of infiltration | Serosa | 59 | 0.581 | 0.891 | 0.267 | 0.184 | 0.102 | 0.9 | 0.13 | 0.025 | 0.184 | 0.083 | 0.119 | 0.058 | 0.253 | 0.207 | 0.227 | 0.173 | Muscular | 21 | Mucosal and submucosal | 0 | Differentiation | Poorly | 25 | 0.76 | 0.36 | 0.53 | 0.289 | 0.151 | 0.519 | 0.24 | 0.081 | 0.351 | 0.271 | 0.426 | 0.139 | 0.497 | 0.647 | 0.334 | 0.157 | Moderately | 40 | High | 15 |
|
|