Pyroptosis Patterns Are Involved in Immune Microenvironment Regulation of Dilated Cardiomyopathy

Figure 3

Association of PRGs with immune cells and immune response pathways. (a) The dot plot shows the correlation between each infiltrating cell and each hub PRG in the dysregulated immune microenvironment. The most positive interrelated immune cell-hub PRG pair was GSDMD-pDCs, and the violin plot on the right shows the expression or fraction status. The most negatively correlated immune cell-hub PRG pair was GSDMD-Tregs, and the violin plot on the left shows the expression or fraction status. (b) The dot plot shows the association between each gene set of the immune dysregulation response and the 12 hub PRGs. The most positively correlated pair was CASP1-parainflammation, and the violin plot in the right shows the expression or activity. The most negative interrelated pair was CASP9-type_II_IFN_response, and the violin plot on the right shows the expression or activity.

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