Pyroptosis Patterns Are Involved in Immune Microenvironment Regulation of Dilated Cardiomyopathy

Figure 7

Identification and functional analysis of genes involved in the pyroptosis phenotype in DCM. (a) 2142 genes were related to the pyroptosis phenotype. (b) GO-BP functional enrichment analysis showed the biological features of genes involved in the pyroptosis phenotype. (c) GO enrichment analysis of genes related to the pyroptosis phenotype revealed the correlation between PRGs and immune mechanisms. (d) Sample clustering was performed on the strength of the expression information of all samples. All differentially expressed genes with were used for WGCNA. (e) Analysis of the scale-free ft index and analysis of the mean connectivity for various soft-thresholding powers. (f) Gene tree diagram. The coloured line below the tree diagram shows the modules determined using dynamic tree cutting. (g) Heat map of the relevance between the characteristic genes of the module and the pyrolysis pattern. (h) Gene significance (GS) scatter plot of pyrolysis pattern A and module member (MM) in the magenta module.

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