Prognostic Value of Histidine-Rich Glycoprotein for Community-Acquired Pneumonia

Table 2

AUC and threshold for predicting 30-day mortality in patients with CAP based on different parameters.

Parameter	Threshold	Sensitivity (%)	Specificity (%)	AUC	value	95% CI
						Lower limit	Higher limit
Age (years)	>61	72.70	63.90	0.698	0.003	0.620	0.768
Bilateral lung infection	Bilateral	90.91	40.82	0.659	0.027	0.579	0.732
PCT (μg/L)	>2.91	63.64	80.27	0.705	0.020	0.627	0.775
IL-6 (pg/mL)	>79.69	90.91	70.07	0.842	< 0.001	0.776	0.895
CURB-65	> 1	72.73	74.83	0.813	< 0.001	0.743	0.870
PSI	> 103	90.91	78.91	0.874	< 0.001	0.811	0.921
APACHE II	> 11	100	78.23	0.923	< 0.001	0.869	0.959
HRG (μg/mL)	≤ 16.92	100	72.79	0.810	< 0.001	0.740	0.868

Abbreviations: APACHE: acute physiology and chronic health evaluation; AUC: area under the curve; CAP: community-acquired pneumonia; CI: confidence interval; CURB-65: confusion, urea, respiratory rate, blood pressure, and years old; HRG: histidine-rich glycoprotein; IL-6: interleukin-6; PCT: procalcitonin; PSI: pneumonia severity index.