Prognostic Value of Histidine-Rich Glycoprotein for Community-Acquired Pneumonia

Table 3

Cox proportional hazard regression analysis of the effects of multiple variables on 30-day survival of patients with CAP.

Variables	Univariate analysis		Multivariate analysis
	HR (95% CI)	value	HR (95% CI)	value
Age	1.040 (1.000–1.082)	0.048
Bilateral lung infection	4.387 (0.557–34.567)	0.160
PCT (μg/L)	1.033 (1.001–1.066)	0.046
IL-6 (pg/mL)	1.000 (1.000–1.000)	0.001	1.001 (1.000–1.001)	0.001
CURB-65	1.864 (1.198–2.900)	0.006
PSI	1.029 (1.011–1.047)	0.002
APACHE II	1.397 (1.204–1.622)	< 0.001	2.020 (1.338–3.048)	0.001
HRG (μg/mL)	0.949 (0.900–0.999)	0.047	0.889 (0.791–0.999)	0.049

Abbreviations: APACHE: acute physiology and chronic health evaluation; CAP: community-acquired pneumonia; CI: confidence interval; CURB-65: confusion, urea, respiratory rate, blood pressure, and old; HR: hazard ratio; HRG: histidine-rich glycoprotein; IL-6: interleukin-6; PCT: procalcitonin; PSI: pneumonia severity index.