Predicting Prognosis of Hepatocellular Carcinoma Patients Based on the Expression Signatures of Mitophagy Genes

Figure 3

Validation prognostic characteristic of the 8-gene signature model in the ICGC cohort. (a) Distribution and median values of risk scores in the ICGC cohort. (b) PCA between the high-risk group and low-risk group in the ICGC cohort. (c) t-SNE analysis between the high-risk group and low-risk group in the ICGC cohort. (d) With the increasing of risk scores, the distribution of patient survival status in the ICGC cohort. (e) Overall survival of patients between the high-risk group and low-risk group in the ICGC cohort. (f) AUC of time-dependent ROC curves verified the prognostic performance of the risk score in the ICGC cohort. AUC: area under curve; PCA: principal component analysis; ROC: receiver operating characteristic curve; t-SNE: t-distributed stochastic neighbor embedding; ICGC: International Cancer Genome Consortium.

(a)

(b)

(c)

(d)

(e)

(f)