Research Article
Predicting Prognosis of Hepatocellular Carcinoma Patients Based on the Expression Signatures of Mitophagy Genes
Table 2
Baseline characteristics of HCC patients in different risk groups.
| | TCGA cohort | | ICGC cohort | | | Variables | Cases | High risk (%) | Low risk (%) | value | Cases | High risk (%) | Low risk (%) | value |
| | Gender | 365 | | | | 231 | | | | | Male | 246 | 128 (52.0) | 118 (48.0) | | 170 | 88 (51.8) | 82 (48.2) | | | Female | 119 | 54 (45.4) | 65 (54.6) | 0.233 | 61 | 27 (44.3) | 34 (55.7) | 0.315 | | Age (years) | 365 | | | | 231 | | | | | >65 | 138 | 68 (49.3) | 70 (50.7) | | 142 | 72 (50.7) | 70 (49.3) | | | ≤65 | 227 | 114 (50.2) | 113 (49.8) | 0.816 | 89 | 43 (48.3) | 46 (51.7) | 0.724 | | Grade | 360 | | | | — | | | | | G1+G2 | 230 | 96 (41.7) | 134 (58.3) | | — | — | — | | | G3+G4 | 130 | 84 (64.6) | 46 (35.4) | <0.001 | — | — | — | — | | Invasive extent | 362 | | | | — | | | | | T1-2 | 271 | 129 (47.6) | 142 (52.4) | | — | — | — | | | T3-4 | 91 | 53 (58.2) | 38 (41.8) | 0.079 | — | — | — | — | | TNM stage | 341 | | | | 231 | | | | | I+II | 254 | 119 (46.9) | 135 (53.1) | | 141 | 60 (42.6) | 81 (57.4) | | | III+IV | 87 | 50 (57.5) | 37 (42.5) | 0.087 | 90 | 55 (61.1) | 35 (38.9) | 0.006 |
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HCC: hepatocellular carcinoma; ICGC: International Cancer Genome Consortium; TCGA: The Cancer Genome Atlas.
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