miR-657 Targets SRCIN1 via the Slug Pathway to Promote NSCLC Tumor Growth and EMT Induction

Figure 1

NSCLC tissues exhibit miR-657 upregulation that is predictive of poor prognostic outcomes. (a) miR-657 expression in NSCLC patient tumors and normal (paracancerous) tissues was measured via qPCR, with a normal tissue being used for normalization, . (b) miR-657 levels in tissues were measured via FISH. (c) Quantification of the FISH results. (d) The relationship between overall survival and miR-657 expression was examined using the Kaplan-Meier curves. (e) The circulating miR-657 expressions in the blood of NSCLC patients () were significantly increased compared with healthy volunteers (). Data are from three replicate assessments. .

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