Research Article

miR-657 Targets SRCIN1 via the Slug Pathway to Promote NSCLC Tumor Growth and EMT Induction

Figure 2

miR-657 enhances proliferative activity in NSCLC cell lines. (a) qPCR was employed for the appraisal of miR-657 expression in the cell lines of NSCLC and BEAS-2B cells, with control values being used for normalization. (b) qPCR was used to confirm the successful transfection of NCI-H1650 and A549 cells with miR-657 mimics and inhibitors. (c) The viability of NCI-H1650 and A549 cells following miR-657 inhibitor, mimic, or NC transfection was measured. (d and e) The proliferation of H460 and A549 cells transfected as indicated was assessed via EdU assay. Data are from three replicate assessments. , , and .
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