Comprehensive Analysis of Novel Genes and Pathways Associated with Osteogenic Differentiation of Adipose Stem Cells

Table 2

Gene Ontology analyses of downregulated DEGs.

Ontology	ID	Description	GeneRatio	BgRatio	value	.adjust	value
BP	GO: 0010721	Negative regulation of cell development	12/66	344/18670	2.55e-09	5.10e-06	3.85e-06
BP	GO: 0060537	Muscle tissue development	12/66	408/18670	1.71e-08	1.71e-05	1.29e-05
BP	GO: 0014706	Striated muscle tissue development	11/66	390/18670	1.10e-07	7.34e-05	5.54e-05
BP	GO: 0050768	Negative regulation of neurogenesis	9/66	295/18670	9.14e-07	4.57e-04	3.45e-04
BP	GO: 0051961	Negative regulation of nervous system development	9/66	315/18670	1.57e-06	6.29e-04	4.75e-04
CC	GO: 0005913	Cell-cell adherens junction	4/66	117/19717	6.39e-04	0.026	0.024
CC	GO: 0045121	Membrane raft	6/66	315/19717	6.44e-04	0.026	0.024
CC	GO: 0098857	Membrane microdomain	6/66	316/19717	6.55e-04	0.026	0.024
CC	GO: 0098589	Membrane region	6/66	328/19717	7.95e-04	0.026	0.024
CC	GO: 0016342	Catenin complex	2/66	29/19717	0.004	0.092	0.084
MF	GO: 0045499	Chemorepellent activity	4/63	27/17697	2.41e-06	5.22e-04	4.61e-04
MF	GO: 0001158	Enhancer sequence-specific DNA binding	5/63	119/17697	6.50e-05	0.005	0.005
MF	GO: 0030215	Semaphorin receptor binding	3/63	23/17697	7.24e-05	0.005	0.005
MF	GO: 0035326	Enhancer binding	5/63	133/17697	1.10e-04	0.006	0.005
MF	GO: 0005539	Glycosaminoglycan binding	6/63	229/17697	1.61e-04	0.007	0.006
KEGG	hsa04550	Signaling pathways regulating pluripotency of stem cells	5/40	143/8076	6.48e-04	0.064	0.061
KEGG	hsa04350	TGF-beta signaling pathway	4/40	94/8076	0.001	0.064	0.061