Research Article

Dose-Response Associations of Metabolic Score for Insulin Resistance Index with Nonalcoholic Fatty Liver Disease among a Nonobese Chinese Population: Retrospective Evidence from a Population-Based Cohort Study

Table 1

Characteristics of research subjects.

VariableMETS-IR categories
Q1 (18.88-27.66)Q2 (27.66-30.93)Q3 (30.94-34.33)Q4 (34.33-67.05) value

2683268226822683
Age (years)<0.001
Sex<0.001
 Women1331 (49.61%)1225 (45.67%)1172 (43.70%)1111 (41.41%)
 Men1352 (50.39%)1457 (54.33%)1510 (56.30%)1572 (58.59%)
BMI (kg/m2)<0.001
SBP (mmHg)<0.001
DBP (mmHg)<0.001
TC (mmol/L)<0.001
TG (mmol/L)0.83 (0.68-1.05)1.03 (0.82-1.30)1.26 (0.99-1.61)1.87 (1.38-2.55)<0.001
HDL-C (mmol/L)<0.001
FPG (mmol/L)<0.001
LDL-C (mmol/L)<0.001
ALP (U/L)<0.001
GLB (g/L)<0.001
GGT (U/L)18.00 (14.00-23.00)20.00 (16.00-27.00)23.00 (18.00-33.00)29.00 (21.00-44.00)<0.001
ALB (g/L)0.856
ALT (U/L)13.00 (11.00-18.00)15.00 (12.00-20.00)18.00 (13.00-24.00)21.00 (15.00-28.00)<0.001
AST (U/L)20.00 (17.00-23.00)21.00 (18.00-25.00)22.00 (19.00-26.00)23.00 (20.00-27.00)<0.001
TP (g/L)<0.001
BUN (mmol/L)<0.001
Cr (μmol/L)<0.001
UA (mmol/L)<0.001

Variables are presented as the or (%) or median (Q1, Q3). Abbreviations: METS-IR: metabolic score for insulin resistance; SBP: systolic blood pressure; BMI: body mass index; DBP: diastolic blood pressure; TC: total cholesterol; FPG: fasting plasma glucose; HDL-C: high-density lipoprotein cholesterol; TG: triglyceride; LDL-C: low-density lipoprotein cholesterol; AST: aspartate aminotransferase; TP: total protein; ALP: alkaline phosphatase; GLB: globulin; ALB: albumin; Cr: creatinine; BUN: blood urea nitrogen; UA: uric acid; NAFLD: nonalcoholic fatty liver disease.