Dose-Response Associations of Metabolic Score for Insulin Resistance Index with Nonalcoholic Fatty Liver Disease among a Nonobese Chinese Population: Retrospective Evidence from a Population-Based Cohort Study

Table 2

Regression models of effects of METS-IR on new-onset NAFLD.

Exposure	Crude model		Model 1		Model 2
	HR (95% CI)	value	HR (95% CI)	value	HR (95% CI)	value
Q1 (18.88-27.66)	Ref.		Ref.		Ref.
Q2 (27.66-30.93)	4.74 (3.38, 6.65)	<0.001	2.76 (1.95, 3.91)	<0.001	2.69 (1.87, 3.86)	<0.001
Q3 (30.94-34.33)	11.11 (8.06, 15.33)	<0.001	4.56 (3.21, 6.46)	<0.001	4.25 (2.86, 6.30)	<0.001
Q4 (34.33-67.05)	24.34 (17.75, 33.38)	<0.001	7.82 (5.46, 11.21)	<0.001	6.40 (4.06, 10.08)	<0.001
for trend	<0.001		<0.001		<0.001

Crude model adjusted for none. Model 1 adjusted for age, sex, and BMI. Model 2 adjusted for the variables in Model 1 plus ALP, TG, GGT, HDL-C, ALT, BUN, AST, Cr, UA, FPG, SBP, LDL-C, and DBP. Abbreviations: CI: confidence interval; HR: hazard ratio. Other abbreviations as in Table 1.