HSPB1 Gene Variants and Schizophrenia: A Case-Control Study in a Polish Population

Table 1

Comparison of the allele frequencies and genotype distributions of the three HSPB1 SNPs between the SCZ cases and controls in all, women, and men samples.

dbSNP	Genotype/allele	All				Women				Men
		Cases	Controls			Cases	Controls			Cases	Controls
rs2868370	G/G	276 (68.5%)	442 (65%)	2.01	0.37	111 (69%)	212 (66%)	0.26	0.88	165 (68%)	230 (64%)	2.49	0.29
	G/A	111 (27.5%)	214 (31.5%)			46 (28%)	97 (30%)			65 (27%)	117 (33%)
	A/A	16 (4%)	23 (3.5%)			5 (3%)	11 (3%)			11 (5%)	12 (3%)
	G	663 (82%)	1098 (81%)	0.66	0.42	268 (83%)	521 (81%)	0.25	0.62	395 (82%)	577 (80%)	0.47	0.49
	A	143 (18%)	260 (19%)			56 (17%)	119 (19%)			87 (18%)	141 (20%)
rs2868371	C/C	208 (52%)	347 (51%)	0.99	0.61	82 (51%)	155 (48%)	0.24	0.89	126 (52%)	192 (53%)	1.61	0.45
	C/G	170 (42%)	279 (41%)			70 (43%)	143 (45%)			100 (41%)	136 (38%)
	G/G	25 (6%)	53 (8%)			10 (6%)	22 (7%)			15 (6%)	31 (9%)
	C	586 (73%)	973 (72%)	0.28	0.6	234 (72%)	453 (71%)	0.22	0.64	352 (73%)	520 (72%)	0.05	0.82
	G	220 (27%)	385 (28%)			90 (28%)	187 (29%)			130 (27%)	198 (28%)
rs7459185	G/G	226 (56%)	352 (52%)	2.36	0.31	90 (56%)	166 (52%)	0.93	0.63	136 (56%)	186 (52%)	1.38	0.50
	G/C	142 (35%)	271 (40%)			59 (36%)	131 (41%)			83 (34%)	140 (39%)
	C/C	35 (9%)	56 (8%)			13 (8%)	23 (7%)			22 (9%)	33 (9%)
	G	594 (74%)	975 (72%)	0.92	0.34	239 (74%)	463 (72%)	0.22	0.64	355 (74%)	512 (71%)	0.79	0.37
	C	212 (26%)	383 (28%)			85 (26%)	177 (28%)			127 (26%)	206 (29%)