Liraglutide Alleviates Diabetic Atherosclerosis through Regulating Calcification of Vascular Smooth Muscle Cells

Figure 4

LIRA inhibits the osteogenic transformation and calcification of VSMC under high-glucose condition. Protein expression of (a) SMα-actin, (b) OPN, and (c) Cbfα-1. Data from three independent experiments are expressed as deviation. vs. control; vs. HG; vs. HG + LIRA. (d) Calcification of VSMC tested by alizarin red staining (400x). Data from three independent experiments are expressed as deviation; vs. control; vs. HG; , vs. HG + LIRA.

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