Research Article

Elevated IOP Alters the Material Properties of Sclera and Lamina Cribrosa in Monkeys

Table 6

Initial rate and equilibrium rate of creep of ppSCl in circumferential direction (μm/min, Int: initial rate; Equl: equilibrium rate).

GroupsRate of creep (μm/min)
SuperiorInferiorNasalTemporal

Exp. (Int.)54.590.001
Ctrl. (Int.)10.530.023
0.0210.0180.0250.017
Exp. (Equl.)55.430.001
Ctrl. (Equl.)5.560.066#
0.0060.0130.0160.045

Creep rate of each scleral trip was measured for 3 times repeatedly. Paired-samples test was applied in the intergroup comparison in each quadrant; ANOVA method and post hoc test (LSD, Tukey HSD) were applied in the intragroup comparison in each group. The initial rate and equilibrium rate of each quadrant were lower in the experimental group than that in the control group, with significant difference (). The initial rate had significant difference between each quadrant in double groups, and equilibrium rate had significant difference between each quadrant in the experimental group (). #The equilibrium rate between each quadrant had no significant difference in the control group ().