Identification of Synovial Fibroblast-Associated Neuropeptide Genes and m6A Factors in Rheumatoid Arthritis Using Single-Cell Analysis and Machine Learning

<div>Single-cell analysis preprocessing and downscaling and clustering process for GSE109449. (a) Data accusations after filtering of genes and cells. (b) Elbow plot showing that the inflection point occurs, suggesting that the first nine PCs can contain most signals. (c) All included cells are grouped into six clusters based on a clustering tree constructed based on the selected nine PCs. (d) Heat map showing the expression of the top 10 marker genes of the six clusters in single-cell samples. (e) Volcano plot showing differences in the expression of neuropeptide-related mRNAs among clustering-related marker genes. Abbreviation: PC: principal component.</div>

Disease Markers

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Figure 1: Identification of Synovial Fibroblast-Associated Neuropeptide Genes and m6A Factors in Rheumatoid Arthritis Using Single-Cell Analysis and Machine Learning 

Figure 1 | Identification of Synovial Fibroblast-Associated Neuropeptide Genes and m6A Factors in Rheumatoid Arthritis Using Single-Cell Analysis and Machine Learning 