Identification of Synovial Fibroblast-Associated Neuropeptide Genes and m6A Factors in Rheumatoid Arthritis Using Single-Cell Analysis and Machine Learning

<div>Combined analysis of screened m6A regulatory genes and DE mRNAs. (a) Venn plot showing the results of intersection analysis of SVM-RFE and DE mRNAs. A total of two m6A regulatory-related genes were screened. (b) Volcano plot showing the results of the differential analysis in bulk RNA. The two m6A regulatory genes are labelled in the graph. (c) Expression levels of <i>IGFBP2</i> and <i>METTL3</i> in UMAP. Abbreviations: DE: differentially expressed; SVM-RFE: support vector machine-recursive feature elimination.</div>

Disease Markers

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Figure 4: Identification of Synovial Fibroblast-Associated Neuropeptide Genes and m6A Factors in Rheumatoid Arthritis Using Single-Cell Analysis and Machine Learning 

Figure 4 | Identification of Synovial Fibroblast-Associated Neuropeptide Genes and m6A Factors in Rheumatoid Arthritis Using Single-Cell Analysis and Machine Learning 