Association of Polymorphisms in NHEJ Pathway Genes with HIV-1 Infection and AIDS Progression in a Northern Chinese MSM Population

Figure 2

The best four-locus SNP-SNP interaction model identified by the generalized multifactor dimensionality reduction method. High-risk cells are in dark, low-risk cells are in grey, and empty cells are indicated by no shading. In each cell, the left bar represents case while the right bar represents control. The heights of the bars are proportional to the sum of samples in each group. Note that the patterns of high-risk and low-risk cells differ across each of the different multilocus dimensions, presenting evidence of SNP-SNP interaction or epistasis.