Research Article
Association of Polymorphisms in NHEJ Pathway Genes with HIV-1 Infection and AIDS Progression in a Northern Chinese MSM Population
Table 3
The frequencies of haplotypes of NHEJ genes in cases and controls.
| Gene | Haplotype | Frequency | Haplotype frequencies in the cases | Haplotype frequencies in the controls | Chi-square | |
| XRCC6 | TCGG | 0.671 | 0.665 | 0.677 | 0.309 | 0.578 | | TGGG | 0.237 | 0.233 | 0.241 | 0.175 | 0.675 | CCAC | 0.070 | 0.081 | 0.060 | 3.181 | 0.075 | CCGC | 0.021 | 0.021 | 0.022 | 0.012 | 0.912 | XRCC5 | Block 1 | | | | | | | GG | 0.771 | 0.777 | 0.765 | 0.335 | 0.563 | TA | 0.223 | 0.219 | 0.227 | 0.169 | 0.681 | Block 2 | | | | | | TG | 0.468 | 0.470 | 0.466 | 0.040 | 0.841 | AG | 0.452 | 0.448 | 0.456 | 0.149 | 0.699 | TA | 0.080 | 0.082 | 0.078 | 0.115 | 0.735 | Block 3 | | | | | | TA | 0.693 | 0.705 | 0.683 | 1.101 | 0.294 | CG | 0.165 | 0.164 | 0.166 | 0.009 | 0.923 | TG | 0.142 | 0.132 | 0.152 | 1.649 | 0.199 | XRCC4 | Block 1 | | | | | | | TG | 0.806 | 0.806 | 0.805 | 0.007 | 0.931 | TT | 0.141 | 0.135 | 0.147 | 0.597 | 0.440 | GT | 0.053 | 0.059 | 0.048 | 1.095 | 0.295 | Block 2 | | | | | | CT | 0.555 | 0.536 | 0.573 | 2.552 | 0.110 | TT | 0.308 | 0.327 | 0.290 | 3.095 | 0.079 | CC | 0.133 | 0.132 | 0.134 | 0.020 | 0.888 | LIG4 | GG | 0.814 | 0.815 | 0.812 | 0.035 | 0.852 | | AA | 0.102 | 0.101 | 0.104 | 0.030 | 0.863 | AG | 0.084 | 0.084 | 0.084 | 0.005 | 0.941 |
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