Research Article

Crosslinking-Induced Corneal Endothelium Dysfunction and Its Protection by Topical Ripasudil Treatment

Figure 1

CXL irradiation causes corneal edema in mice. Representative slit-lamp images showing differences between the 5 different groups at time points corresponding to 36 h, 4 d, 7 d, and 14 d after CXL treatment. (a) Time-dependent changes in corneal opacity scores in the 5 groups. Data are expressed as the ; . ; . (b) U(-), R(-): neither UVA norriboflavin; U(++), R(+): 1.08 J/cm2 UVA; U(-), R(+): riboflavin only; U(+), R(+): 0.54 J/cm2 UVA plus riboflavin; U(++), R(+): 1.08 J/cm2 UVA plus riboflavin.
(a)
(b)