Research Article

Clinical Significance of Circulating Tumor Cells (CTCs) and Survivin on Predicting Prognosis in Thyroid Cancer Patients

Table 1

Relationship between the presence of circulating tumor cells (CTCs) and the clinical features of thyroid cancer.

Number of casesCTC-positive (%)CTC-negative (%) values

Age
≤60 years old93 (56.7%)54 (58.1%)39 (42.9%)1.720.46
>60 years old71 (43.3%)52 (73.3%)19 (26.7%)
Gender
Female104 (63.4%)62 (59.6%)12 (40.5%)0.0150.56
Male60 (36.6%)30 (50.0%)30 (50.0%)
Pathological subtypes0.001
PTC73 (44.5%)12 (16.4%)61 (83.6%)10.63
FTC60 (36.6%)14 (23.3%)6 (76.7%)
MTC12 (7.3%7 (58.3%)5 (41.6%)
PDTC10 (6.1%)9 (90.0%)1 (10.0%)
ATC9 (5.5)9 (100.0%)0 (0.00%)
TNM stages
I101 (61.4%)9 (8.9%)92 (91.1%)10.630.001
II30 (18.4%)15 (50.0%)15 (50.0%)
III22 (13.5%)18 (81.8%)4 (18.2%)
IV11 (6.7%)11 (100.0%)0 (0.00%)

CTC: circulating tumor cell; PTC: papillary thyroid cancer; FTC: follicular thyroid cancer; MTC: medullary thyroid cancer; PDTC: poorly differentiated thyroid cancer; ATC: anaplastic thyroid cancer.