Ginsenoside Rb1 Modulates the Migration of Bone-Derived Mesenchymal Stem Cells through the SDF-1/CXCR4 Axis and PI3K/Akt Pathway

<div>Ginsenoside Rb1 facilitated the migration of BMSCs. The BMSCs were incubated with different concentrations of ginsenoside Rb1 (0, 10, and 20 <i>μ</i>g/mL, respectively). (a) Representative images of the wound-healing assay in different groups, and wound sites were observed and photographed at 0 and 24 h (×200 original magnification). (b) Representative images of the Transwell assay in different groups, and cells migrated from the upper chamber to the bottom surfaces were stained with crystal violet and observed under a microscope (×200 original magnification). (c) Quantitative results of the wound-healing assay. (d) Quantitative results of the Transwell assay. Tests were performed at least three times. 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Disease Markers

fig2

Figure 2

Figure 2: Ginsenoside Rb1 Modulates the Migration of Bone-Derived Mesenchymal Stem Cells through the SDF-1/CXCR4 Axis and PI3K/Akt Pathway 