Research Article
The Association of Serum Neurofilament Light Chain and Acute Ischaemic Stroke Is Influenced by Effective Revascularization
| | Total | Revascularized | Nonrevascularized | value |
| | Demographic data | | Age, median (IQR) (y) | 66.00 (18.25) | 66.00 (18.00) | 66.00 (18.00) | 0.939 | | Female, (%) | 46 (40.70) | 20 (46.50) | 26 (37.10) | 0.333 |
| | Laboratory values, median (IQR) (pg/mL) | | ln(sNfL) | 3.39 (1.76) | 3.08 (1.46) | 3.81 (1.70) | 0.014 |
| | Medical history, (%) | | Heart disease | 44 (38.90) | 22 (51.20) | 22 (34.10) | 0.072 | | Hypertension | 66 (58.40) | 27 (62.80) | 39 (55.70) | 0.692 | | Diabetes | 33 (29.20) | 9 (20.90) | 24 (34.30) | 0.137 | | Smoke history | 34 (30.10) | 15 (34.90) | 19 (27.10) | 0.527 | | Drink history | 33 (29.20) | 18 (41.90) | 15 (21.40) | 0.034 | | Stroke history | 23 (20.40) | 10 (23.30) | 13 (18.60) | 0.636 |
| | Clinical data, median (IQR) | | ASPECT scores | 12.00 (3.00) | 10.00 (3.00) | 13.00 (1.75) | 0.001 | | NIHSS admission | 8.00 (10.00) | 14.00 (10.00) | 6.00 (6.00) | 0.005 | | NIHSS (7D) | 4.00 (9.00) | 3.00 (13.00) | 3.00 (7.00) | 0.162 | | Good prognosis, (%) | 78 (70.90) | 28 (75.68) | 50 (64.94) | 0.165 | | Arrival time | 7.00 (20.50) | 4.00 (4.00) | 15.00 (18.00) | <0.001 |
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sNfL: serum neurofilament light chain; ASPECT: Alberta Stroke Program Early CT; NIHSS: National Institutes of Health Stroke Scale; mRS: modified Rankin Scale. Prognosis (good prognosis, mRS scores 0-2; poor prognosis, mRS scores 3-6).
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