The Association of Serum Neurofilament Light Chain and Acute Ischaemic Stroke Is Influenced by Effective Revascularization
Table 3
Associations between ln(sNfL) and clinical severity (NIHSS scores).
NIHSS admission
Total
Revascularized
Nonrevascularized
value
(95% CI)
value
(95% CI)
value
(95% CI)
Univariate for ln(sNfL)
0.875
0.015 (-0.182-0.212)
0.037
-0.346 (-0.590--0.079)
0.007
0.313 (0.096-0.506)
Multivariate for ln(sNfL)
0.293
0.019 (-0.020-0.0.050)
0.729
-0.013 (-0.080-0.060)
0.005
0.057 (0.019-0.060)
NIHSS (7D)
Univariate for ln(sNfL)
0.003
0.279 (0.074-0.447)
0.568
-0.098 (-0.432-0.269)
<0.001
0.386 (0.188-0.547)
Multivariate for ln(sNfL)
0.004
0.041 (0.012-0.068)
0.967
0.002 (-0.064-0.077)
0.003
0.047 (0.019-0.085)
NIHSS (admission-7D)
Univariate for ln(sNfL)
<0.001
-0.370 (-0.501--0.216)
0.080
0.023 (-0.548-0.084)
0.010
-0.299 (-0.475--0.083)
Multivariate for ln(sNfL)
0.017
-0.049 (-0.083--0.018)
0.606
-0.019 (-0.079-0.068)
0.083
-0.051 (-0.138-0.004)
Adjusted for age, sex, stroke history, and the time between the onset of illness and arrival at hospital. sNfL: serum neurofilament light chain; 7D: 7 days after stroke; NIHSS: National Institutes of Health Stroke Scale.
